J Med Assoc Thai 2010; 93 (9):1107

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Bilateral Septic Cavernous Sinus Thrombosis Following the Masticator and Parapharyngeal Space Infection from the Odontogenic Origin: A Case Report
Kiddee W Mail, Preechawai P , Hirunpat S

Neglect of odontogenic infections can have serious consequences. If they spread through fascial planes and
intracranially they can cause an abscess, orbital cellulitis, and eventually cavernous sinus thrombosis. The authors report a
case of rapid progressive bilateral orbital cellulitis and cavernous sinus thrombosis that originated from dental caries. Septic
cavernous sinus thrombosis is a medical emergency. Early recognition and prompt treatments direct to the underlying
sources of infection are crucial. Broad-spectrum intravenous antibiotics are the mainstay of treatment to reduce morbidity
and mortality from this lethal condition. Management should be based on early diagnosis and prompt management with
intravenous broad-spectrum antibiotics and surgical intervention.

Keywords: Dental infection, Parapharyngeal space infection, Orbital cellulitis, Septic cavernous sinus thrombosis, Antibiotic
therapy, Pseudomonas aeruginosa

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