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Original ArticleOpen Access
Drug-Eluting Stent for Unprotected Left Main Coronary Artery Disease: Early and Mid-Term Outcomes
Tassanawiwat W ,
Mahavanakul W ,
Thanakitcharu P ,
Komolsart P ,
Chansod S ,
Sookananchai B ,
Wongvipaporn C ,
Kiatchoosakun S ,
Cheiniwat S ,
Tresukosol D
Background: PCI is increasingly performed in patients with ULMCA disease. The efficacy and safety of drug-eluting stents
in ULMCA disease have been reported.
Objective: To evaluate the early and mid-term clinical outcome of the Percutaneous Coronary Intervention (PCI) with Drug-
Eluting stent (DES) in unprotected left main coronary artery (ULMCA) disease patients.
Material and Method: PCI with DES was performed with 90 consecutive patients having ULMCA disease between January
2006 and June 2009.
Results: At a median follow-up of 22.8 + 12.2 months, major adverse cardiac or cerebrovascular events (MACCE) occurred
in 11 (12.2%) patients. There were seven (7.8%) deaths including two (2.2%) cardiac deaths and five (5.6%) non-cardiac
deaths. There was one MI (1.1%), and four (4.4%) target vessel revascularization. Restenosis in the left main occurred only
in two patients (2.2%) and definite stent thrombosis occurred in two patients (2.2%).
Conclusion: The present study demonstrates that PCI with Drug-Eluting stent implantation in unprotected left main coronary
artery disease is a safe form of treatment and has favorable outcomes.
Keywords: Left main, Drug Eluting stent
in ULMCA disease have been reported.
Objective: To evaluate the early and mid-term clinical outcome of the Percutaneous Coronary Intervention (PCI) with Drug-
Eluting stent (DES) in unprotected left main coronary artery (ULMCA) disease patients.
Material and Method: PCI with DES was performed with 90 consecutive patients having ULMCA disease between January
2006 and June 2009.
Results: At a median follow-up of 22.8 + 12.2 months, major adverse cardiac or cerebrovascular events (MACCE) occurred
in 11 (12.2%) patients. There were seven (7.8%) deaths including two (2.2%) cardiac deaths and five (5.6%) non-cardiac
deaths. There was one MI (1.1%), and four (4.4%) target vessel revascularization. Restenosis in the left main occurred only
in two patients (2.2%) and definite stent thrombosis occurred in two patients (2.2%).
Conclusion: The present study demonstrates that PCI with Drug-Eluting stent implantation in unprotected left main coronary
artery disease is a safe form of treatment and has favorable outcomes.
Keywords: Left main, Drug Eluting stent
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