J Med Assoc Thai 2010; 93 (9):1030

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Drug-Eluting Stent for Unprotected Left Main Coronary Artery Disease: Early and Mid-Term Outcomes
Tassanawiwat W Mail, Mahavanakul W , Thanakitcharu P , Komolsart P , Chansod S , Sookananchai B , Wongvipaporn C , Kiatchoosakun S , Cheiniwat S , Tresukosol D

Background: PCI is increasingly performed in patients with ULMCA disease. The efficacy and safety of drug-eluting stents
in ULMCA disease have been reported.

Objective: To evaluate the early and mid-term clinical outcome of the Percutaneous Coronary Intervention (PCI) with Drug-
Eluting stent (DES) in unprotected left main coronary artery (ULMCA) disease patients.

Material and Method: PCI with DES was performed with 90 consecutive patients having ULMCA disease between January
2006 and June 2009.

Results: At a median follow-up of 22.8 + 12.2 months, major adverse cardiac or cerebrovascular events (MACCE) occurred
in 11 (12.2%) patients. There were seven (7.8%) deaths including two (2.2%) cardiac deaths and five (5.6%) non-cardiac
deaths. There was one MI (1.1%), and four (4.4%) target vessel revascularization. Restenosis in the left main occurred only
in two patients (2.2%) and definite stent thrombosis occurred in two patients (2.2%).

Conclusion: The present study demonstrates that PCI with Drug-Eluting stent implantation in unprotected left main coronary
artery disease is a safe form of treatment and has favorable outcomes.

Keywords: Left main, Drug Eluting stent

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