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Original ArticleOpen Access

Clinical Profiles of Thai Patients with Ocular Myasthenia Gravis in Siriraj Hospital

Leeamornsiri S , Chirapapaisan N , Chuenkongkaew W

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Leeamornsiri S, Chirapapaisan N, Chuenkongkaew W. Clinical Profiles of Thai Patients with Ocular Myasthenia Gravis in Siriraj Hospital. J Med Assoc Thai 2011;94:1117.

Ninety-six patients with ocular myasthenia gravis (OMG) seen at Siriraj Hospital during 1994 to 2004 wereretrospectively reviewed. There were 59 female (61.5%) and 37 (38.5%) male patients with mean ages of 39.5 and 33.8 years,respectively. Patients presented with initial symptoms of only ptosis in 46.9%, only diplopia in 13.5% and both ptosis anddiplopia in 39.6%. However, diplopia alone is uncommon in childhood OMG. Fifteen percent developed systemic symptomswithin two years of diagnosis. Thyroid function test was abnormal in 27.5% of investigated patients. Most abnormalities werehyperthyroidism. Thymoma associated with OMG is a rare condition. Most purely OMG patients can control the disease bypyridostigmine, prednisolone or immunosuppressive drugs.
Keywords: Ocular myasthenia gravis, Ptosis, Diplopia, Pyridostigmine, Generalized myasthenia gravis

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