J Med Assoc Thai 2010; 93 (12):294

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NK/T Cell Lymphoma, Nasal Type with Sinonasal Mass and Palatal Ulcer: A Clinical Case Report and Review of Treatment
Kanitsap N Mail, Warnnissorn N

Extranodal Nasal NK/T cell lymphoma, relatively uncommon type of non-Hodgkin’s lymphoma, is highly aggressive
disease with poor outcomes. Early stage disease may response to radiotherapy alone. However the treatments are usually
chemotherapy and radiotherapy combination and late stage disease may not response to any available therapy. We reported
a 45-year-old woman with extranodal nasal type NK/T cell lymphoma. The patient presented with chronic nasal stuffiness and
mucous bloody discharge. The nasal mass is extensively involved periorbital and sinonasal soft tissue. Due to the extensively
involved of tumor, combination chemotherapy was used to induce response. This patient was involved by complicated
infection and palatal ulcer with likely perforation. The salvage chemotherapy was given and the treatment of NK/T cell
lymphoma from other reports and literatures were reviewed.

Keywords: Lymphoma, NK/T cell, Nasal type


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