Objective: The present study aimed to review the outcomes of 10 years’ experience of laparoscopic hepatectomies at Rajavithi Hospital, a supertertiary hospital.

Materials and Methods: The medical records were reviewed of all patients who underwent laparoscopic hepatectomy at Rajavithi Hospital between January 2006 and December 2015. The outcomes of laparoscopic hepatectomies, the rates of conversion to open procedures, postoperative complications, and patient survival were analyzed.

Results: A total of 127 patients underwent laparoscopic hepatectomy, but medical records were complete in only 90 cases. Most of the patients were males (63.3%) diagnosed with malignant diseases and with many underlying disorders. The most common diseases were hepatocellular carcinoma, HCC, (44.4%), and colorectal liver metastasis (32.2%). Major hepatectomy was performed in one third of patients. The rate of conversion to open procedures was 32.2%, the median blood loss was 900 mL, and median length of hospital stay was 6.5 days. Post-operative complications were occurred in 21.1% of patients, with respiratory complications being the most common. The thirty-day mortality rate was 3.3%.

Conclusion: The conversion rates of our series were relatively high, probably because the majority of our subjects were complicated malignancy patients. To improve the outcomes, selecting patients using appropriate criteria and multidisciplinary care is essential.

Keywords: Laparoscopic hepatectomy, Hepatectomy, Hepatocellular carcinoma, Cholangicarcinoma, Liver metastasis