This article aimed to present a case of 22 year-old Thai female with cleft lip and palate who had malocclusion developed from dental problems, skeletal disharmony and unrepaired alveolar cleft. The treatment was orthodontic combined with one-stage surgical correction which corrected skeletal discrepancy and alveolar cleft in single operation. After treatment, the patient had improved in facial esthetics, attaining good occlusal function and continuous maxillary dental arch. This procedure can reduce morbidity, preclude a second hospitalization and the cost of two-stage surgical correction. However, this is only an alternative treatment for adult cleft patients who need late alveolar bone graft and orthognathic surgery.

Keywords: Cleft lip and palate, Orthodontic treatment, Orthognathic surgery, Simultaneous alveolar bone graft