J Med Assoc Thai 2008; 91 (7):968

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Serum Calcium, Magnesium and Uric Acid in Preeclampsia and Normal Pregnancy
Punthumapol C Mail, Kittichotpanich B

Objective: To compare serum calcium, magnesium and uric acid in mild, severe preeclamptic women and
normal pregnant women.

Study design:
Cross-sectional study.

Setting:
Section of Obstetrics and Gynecology, Taksin Hospital.

Material and Method:
The data was collected from 36 normal pregnant women, 35 mild preeclamptic women
and 33 severe preeclamptic women who were admitted in the Section of Obstetrics and Gynecology at Taksin
Hospital between April 2006 and June 2007. The blood samples were collected and analyzed for calcium,
magnesium and uric acid. The data was analyzed using Analysis of Variances (ANOVA).

Results: The serum calcium in severe preeclamptic women was significantly lower (8.7 + 0.59 mg/dl vs. 8.99
+ 0.31 mg/dl, p = 0.045; and 9.05 + 0.52 mg/dl, p = 0.014) and serum uric acid was significantly higher (7.01
+ 1.93 mg/dl vs. 5.33 + 1.23 mg/dl, p < 0.001 and 5.95 + 1.9 mg/dl, p = 0.044 ) than in normal pregnant women
and mild preeclamptic women respectively, but there was no difference between normal and mild preeclamptic
women. There was no difference in serum magnesium among normal pregnancy and both groups of preeclampsia.

Conclusion: Hypocalcemia and hyperuricemia correlated to severe preeclampsia.

Keywords: Serum calcium, Serum magnesium, Serum uric acid, Preeclampsia, Normal pregnancy

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