Material and Method: A Retrospective analytical study of the medical records of primary open-angle glaucoma patients, between January 2006 and April 2008, were reviewed. All subjects underwent a complete eye examination. The CCT measurement was performed by ultrasonic pachymeter. Mean deviation (MD), pattern standard deviation (PSD), cup-to-disc ratio, and the RNFL thickness of each patient were collected. The correlation coefficient between CCT and MD, PSD, cup-to-disc ratio and RNFL thickness was analyzed.

Results: Twenty-six POAG patients (47 eyes) were eligible for the study. Mean age was 60.96±7.44 years. Average CCT was 511.15±29.66 μm. Mean MD and PSD were -10.01± 8.20 and 7.52±4.43 decibel respectively. Mean cup-to-disc ratio was 0.71±0.17. Mean RNFL thickness of superior, inferior, temporal, nasal quadrants and all quadrants were 101.60±28.68, 87.15±32.56, 60.64±14.14, 61.83±13.96 and 77.80±17.58 μm, respectively. There were significant correlations between CCT and MD (r = 0.532, p<0.001), PSD (r = -0.288, p = 0.05), cup-to-disc ratio (r = -0.478, p = 0.001), and average RNFL thickness (r = 0.487, p = 0.001).

Conclusion: There were significant correlations between CCT and visual field parameters, cup-to-disc ratio, and RNFL thickness.

Keywords: Central corneal thickness, Mean deviation, Pattern standard deviation, Retinal nerve fiber layer thickness, Optical coherence tomography