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Original ArticleOpen Access
The Preemptive Analgesic Effect of Celecoxib for Day-Case Diagnostic Laparoscopy
Phinchantra P 
,
Bunyavehchevin S ,
Suwajanakom S ,
Wisawasukmongchol W
,
Bunyavehchevin S ,
Suwajanakom S ,
Wisawasukmongchol W In a randomized trial, the preemptive analgesic effect of celecoxib in 110 infertile women
undergoing day-case diagnostic laparoscopy was studied at King Chulalongkom Memorial Hospital,
Bangkok, Thailand. The patients randomly received either 200 mg celecoxib or placebo orally 2 hours
before diagnostic laparoscopy. The post-operative shoulder pain and wound pain were self assessed and
recorded, using Visual Analogue Scores (VAS) at 1, 2, 4, 12, and 24 hours. Total post-operative anal-
gesic requirements were recorded at 24 hours. The mean Visual Analogue Scores (VAS) of shoulder
pain in celecoxib group was statistically lower than those of the placebo group (p
=
0.04 ). Nevertheless,
the mean VAS of wound pain and the total post-operative analgesic requirements were not significantly
different. It was concluded that the preemptive celecoxib in day-case diagnostic laparoscopy might
have the advantage of decreasing post laparoscopic shoulder pain.
Key word : Celecoxib, Diagnostic Laparoscopy, Analgesic Effect
undergoing day-case diagnostic laparoscopy was studied at King Chulalongkom Memorial Hospital,
Bangkok, Thailand. The patients randomly received either 200 mg celecoxib or placebo orally 2 hours
before diagnostic laparoscopy. The post-operative shoulder pain and wound pain were self assessed and
recorded, using Visual Analogue Scores (VAS) at 1, 2, 4, 12, and 24 hours. Total post-operative anal-
gesic requirements were recorded at 24 hours. The mean Visual Analogue Scores (VAS) of shoulder
pain in celecoxib group was statistically lower than those of the placebo group (p
=
0.04 ). Nevertheless,
the mean VAS of wound pain and the total post-operative analgesic requirements were not significantly
different. It was concluded that the preemptive celecoxib in day-case diagnostic laparoscopy might
have the advantage of decreasing post laparoscopic shoulder pain.
Key word : Celecoxib, Diagnostic Laparoscopy, Analgesic Effect
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