J Med Assoc Thai 2002; 85 (4):438

Views: 1,463 | Downloads: 22 | Responses: 0

PDF XML Respond to this article Print Alert & updates Request permissions Email to a friend


Dose-Expanded Study in the Reinforcement of Efficacy of Simvastatin
Vichayanrat A Mail

Two hundred and twenty two hyperlipidemic patients were recruited for a 12-week pro-
spective, multicenter, open-label, titrate-to-goal study to evaluate the efficacy and safety of 20 to
40 mg per day of simvastatin in a Thai population. The efficacy on lipid lowering was evaluated
at 4 weeks and 8 weeks after medication. Based on NCEP A TP II guideline and ADA position
statement, subjects were categorized into three groups according to LDL-C goals; group 1: patients
without CHD and with

Download: PDF