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Original ArticleOpen Access
Therapeutic Effects of Aloe vera on Cutaneous Microcirculation and Wound Healing in Second Degree Burn Model in Rats
Somboonwong J 
,
Thanamittramanee S ,
Jariyapongskul A ,
Patumraj S
,
Thanamittramanee S ,
Jariyapongskul A ,
Patumraj S Objective : To demonstrate the microcirculatory and wound healing effects of
Aloe
rem
on induced second degree burn wounds in rats.
Method : A total of 48 male Wistar rats were equally divided into 4 groups as follows :
sham controls, untreated burn-wound rats, those treated with once-daily application of normal
saline (NSS) and those treated with once-daily application of lyophilized
Aloe vera
gel. The
animals in each group were equally subdivided into 2 subgroups for the study of cutaneous micro-
circulation and wound healing on day 7 and 14 after burn. Dorsal skinfold chamber preparation
and intravital fluorescence microscopic technique were performed to examine demwl microvas-
cular changes, including arteriolar diameter, postcapillary venular permeability and leukocyte
adhesion on postcapillary venules.
Results : On day 7, the vasodilation and increased postcapillary venular permeability as
encountered in the untreated burn were found to be reduced significantly (p
Aloe
rem
on induced second degree burn wounds in rats.
Method : A total of 48 male Wistar rats were equally divided into 4 groups as follows :
sham controls, untreated burn-wound rats, those treated with once-daily application of normal
saline (NSS) and those treated with once-daily application of lyophilized
Aloe vera
gel. The
animals in each group were equally subdivided into 2 subgroups for the study of cutaneous micro-
circulation and wound healing on day 7 and 14 after burn. Dorsal skinfold chamber preparation
and intravital fluorescence microscopic technique were performed to examine demwl microvas-
cular changes, including arteriolar diameter, postcapillary venular permeability and leukocyte
adhesion on postcapillary venules.
Results : On day 7, the vasodilation and increased postcapillary venular permeability as
encountered in the untreated burn were found to be reduced significantly (p
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